Endocrine Abstracts

Erectile failure is a common yet often neglected complication of diabetes that may have a significant negative effect on quality of life and diabetes self-care. I would initially try to ensure a good ascertainment rate of the problem in men attending the diabetes service. I would encourage, though usually fail to persuade men to attend with their partners. I would ascertain the exact nature of the problem, the likely cause, the importance of the problem to the man, the nature ...

Within the adrenal gland, chromaffin cells and their progenitors are exposed to a wide variety of growth factors and hormones, including adrenal androgens such as DHEA. The DHEA producing-zona reticularis of the adrenal cortex is in close proximity to the neural crest-derived catecholamine-producing chromaffin cells of the medulla, enabling strong paracrine interactions. In vivo studies in humans revealed that congenital adrenal hyperplasia due to 21-hydroxylase ...

One important risk factor for the development of arterial hypertension is abdominal obesity. Aldosterone, secreted by adrenocortical cells, promotes sodium and water retention and by that regulates blood pressure homeostasis. Increased serum aldosterone levels have been linked to the development of obesity hypertension. Therefore, identifying the link between obesity and increased aldosterone secretion is of high importance for the management of obesity hypertension.<p cla...